Acne·
PS

Rosacea in Indian Skin: The Underdiagnosed Condition Mistaken for Acne

5 min read Indian Dermatology Online Journal (2023) · Review + 290-subject clinical series · Mumbai and Delhi

The defining clinical distinction: rosacea involves vascular dysregulation of the central face (nose, cheeks, chin) with flushing, telangiectasia, and pustules — but importantly, NO comedones (blackheads or whiteheads). If you see comedones, it is acne. If there are no comedones and flushing is prominent, consider rosacea.

3%
Prevalence estimate
60%
Worsening from acne Rx
0
Comedones in rosacea

Why rosacea is missed in Indian skin

The characteristic central facial redness of rosacea — easily visible as erythema in Fitzpatrick I–II — is masked by melanin in Fitzpatrick IV–VI skin, creating a "dusky" or "uneven" appearance without obvious redness. Indian patients and general practitioners often do not consider rosacea for this reason. The correct diagnostic marker in dark skin: flushing triggered by spicy food/heat, papules and pustules WITHOUT comedones, textural roughness (papulopustular pattern).

Evidence-based rosacea treatment for Indian skin

Rosacea responds to: topical azelaic acid 15% (superior to metronidazole in some trials), topical ivermectin 1%, oral low-dose doxycycline 40mg modified-release (subantimicrobial, anti-inflammatory dose). Standard acne treatments to avoid: benzoyl peroxide (triggers vasodilation), AHA/BHA exfoliants, niacinamide above 5% (can cause transient flushing), strong retinoids early in protocol. Start with azelaic acid + barrier repair only.

Key ingredients · Evidence summary

Azelaic Acid (Rosacea)
Concentration
15% Rx
Efficacy
88%
Ivermectin topical
Concentration
1%
Efficacy
85%
Centella Asiatica
Concentration
5% extract
Efficacy
72%
Green tea extract (EGCG)
Concentration
2–3%
Efficacy
68%
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